Methylamine → HCID 20571388, compound

HRID 126977

Reaction equation

[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([CH:12]([CH3:14])[CH3:13])[C:9](O)=[O:10])=[CH:4][CH:3]=1.C(Cl)(=O)C(Cl)=O.[CH3:21][NH2:22]>>[CH3:21][NH:22][C:9](=[O:10])[CH:8]([C:5]1[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][CH:4]=1)[CH:12]([CH3:14])[CH3:13]

Participants

Reactant 3

HCID 6329Methylamine

HCID 16197Benzeneacetic acid, 4-chloro-alpha-(1-methylethyl)-

HCID 65578Oxalyl chloride

Product 1

HCID 20571388HCID 20571388, compound

Procedure

Following the methods of Example 1, 2-(4-chlorophenyl)-3-methylbutanoic acid is reacted with oxalyl chloride and aqueous methylamine to give N-methyl-2-(4-chlorophenyl)-3-methylbutyramide, which is then combined with 3-phenoxybenzyl bromide and AgBF4, yielding 3-phenoxybenzyl N-methyl-2-(4-chlorophenyl)-3-methylbutanimidate, MS m/e 407 (M+).

Sources & evidence

ORD record: ord-f22e67409f3745d498d28c7d45897e05
Source dataset: uspto-grants-1981_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04254264

Linked notes

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