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Aniline → Aniline

HRID 1285735
Notes
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Reaction equation

HRID 1285735 reaction equation
Brc1cccnc1.Nc1ccccc1>CCN(CC)P1(=NC(C)(C)C)N(C)CCCN1C.CS(=O)(=O)[O][Pd]1(<-[NH2]c2ccccc2-c2cccc[c]21)<-[P](c1ccccc1)(c1ccccc1)c1ccc2ccccc2c1-c1c(P(c2ccccc2)c2ccccc2)ccc2ccccc12.CS(C)=O>c1ccc(Nc2cccnc2)cc1
ParticipantsProcedureWorkupSources & evidenceReaction notes

Participants

9

Reactant 2

HCID 6115AnilineHCID 122863-Bromopyridine

Product 4

HCID 6115AnilineHCID 7095BiphenylHCID 122863-BromopyridineHCID 4712169Phenyl-pyridin-3-yl-amine

Reagents, catalysts & solvents 3

HCID 35138512-((1,1-Dimethylethyl)imino)-N,N-diethylhexahydro-1,3-dimethyl-2lambda5-1,3,2-diazaphosphorin-2-amineReagentHCID 178505363HCID 178505363, compoundReagentHCID 679Dimethyl SulfoxideSolvent4×

Procedure

The Mosquito was used to combine the source plate solutions by multi-aspiration of 250 nL of each of the four reaction components and then to dose the resulting reaction mixture (1 uL) into a 1536-well plate

Workup

  1. additionNo procedure recorded
  2. aliquotNo procedure recorded
  3. additionNo procedure recorded

Sources & evidence

ORD record
ord-e71d7acd24024bd296ca070bcac82101
Source dataset
HTE Pd-catalyzed cross-coupling screen
DOI
10.1126/science.1259203
Original link
View source

Reaction notes

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On this pageParticipantsProcedureWorkupSources & evidenceReaction notes