Hydrochloric Acid → HCID 86734074, compound

Reaction equation

[CH3:1][C:2]1[N:3]=[CH:4][S:5][C:6]=1[CH3:7].C1(NC2CCCCC2)CCCCC1.[S:21]1[CH:25]=[CH:24][CH:23]=[C:22]1[C:26]([OH:28])=[O:27].O.Cl>C(OCC)(=O)C>[CH3:1][C:2]1[N:3]=[CH:4][S:5][C:6]=1[CH3:7].[S:21]1[CH:25]=[CH:24][CH:23]=[C:22]1[C:26]([OH:28])=[O:27]

Participants

Procedure

11.7 g. (0.033 mole) of 4,5-dimethylthiazole-2-thiolcarboxylic acid dicyclohexylamine salt, dissolved in 175 ml. of water and 175 ml. of ethyl acetate, was cooled and acidified with 6N hydrochloric acid to pH 2.2. The layers were separated and the aqueous phase was extracted with 2 × 75 ml. of ethyl acetate. The combined organic phases were dried over magnesium sulfate, filtered and evaporated under reduced pressure yielding 4.6 g. (80%) of a red solid. Infrared spectrum was consistent with the desired material.