Ammonium Hydroxide → 2-Chloro-1,3-thiazole-5-sulfonamide
Reaction equation
[Cl:1][C:2]1[S:3][C:4]([S:7](Cl)(=[O:9])=[O:8])=[CH:5][N:6]=1.[NH4+:11].[OH-]>CCN(CC)CC>[Cl:1][C:2]1[S:3][C:4]([S:7]([NH2:11])(=[O:9])=[O:8])=[CH:5][N:6]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
Prepared by general procedure III from 2-Chloro-thiazole-5-sulfonyl chloride (1.1 g, 5 mmol) and NH4OH (0.42 mL, 6 mmol) with Et3N (0.77 mL, 6 mmol to give the title compound as alight-brown solid (610 mg, 61%). MS (ISN) 197[(M−H)−.
Sources & evidence
- ORD record
- ord-0fcd68ac7d51416db0a6b77d76e03411
- Source dataset
- uspto-grants-2007_07
- Patent number
- US07238808B2
Reaction notes
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