Nitrogen → 2-Isopropyl-5-methylhexanal
Reaction equation
[CH:1]([C:4](=[CH:7][CH2:8][CH:9]([CH3:11])[CH3:10])[CH:5]=[O:6])([CH3:3])[CH3:2].C([O-])(O)=O.[Na+].N#N>[Pd].C(O)C>[CH:1]([CH:4]([CH2:7][CH2:8][CH:9]([CH3:11])[CH3:10])[CH:5]=[O:6])([CH3:3])[CH3:2]Participants
6
Reactant 3
Product 1
Reagents, catalysts & solvents 2
Procedure
To 10 g 2-isopropyl-5-methyl-2-hexenal synthesized above were added 70 ml ethanol, 1 ml saturated NaHCO3 solution and 0.25 g 10% Pd on carbon. N2 was introduced, follwed by H2, and the apparatus was connected with a graduated titration tube filled with H2. The reaction was allowed to continue with stirring at room temperature and atmosphere pressure until the absorption of H2 reached calculation value. The reaction mixture was filtered and the filtrate was used in the next step.
Workup
- customthe apparatus was connected with a graduated titration tube
- additionfilled with H2
- customatmosphere pressure until the absorption of H2 reached calculation value
- filtrationThe reaction mixture was filtered
Sources & evidence
- ORD record
- ord-83c0131379074ee7bbeb4057ca6c9922
- Source dataset
- uspto-grants-2008_06
- Patent number
- US07388061B2
Reaction notes
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