Formic Acid → N-(4-chloro-3-hydroxy-1-phenylbutan-2-yl)benzamide

HRID 134847

Reaction equation

HRID 134847 reaction equation
[C:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)(=[O:8])[NH:9][CH:10]([C:11]([CH2:12][Cl:13])=[O:14])[CH2:15][c:16]1[cH:17][cH:18][cH:19][cH:20][cH:21]1.[CH2:22]([N:23]([CH2:24][CH3:25])[CH2:26][CH3:27])[CH3:28].[CH3:32][CH2:33][O:34][C:35](=[O:36])[CH3:37].[CH:29]([OH:30])=[O:31].[Cl:64][Rh+:65][C:66]1=[C:74]([CH3:75])[C:72]([CH3:73])=[C:70]([CH3:71])[C:67]1([CH3:68])[CH3:69].[c:38]1([CH3:39])[cH:40][cH:41][c:42]([S:43]([NH:44][CH:45]([c:46]2[cH:47][cH:48][cH:49][cH:50][cH:51]2)[CH:52]([c:53]2[cH:54][cH:55][cH:56][cH:57][cH:58]2)[NH2:59])(=[O:60])=[O:61])[cH:62][cH:63]1>>[C:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)(=[O:8])[NH:9][CH:10]([CH:11]([CH2:12][Cl:13])[OH:14])[CH2:15][c:16]1[cH:17][cH:18][cH:19][cH:20][cH:21]1

Participants

7

Reactant 6

HCID 284Formic AcidHCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 3608242N-(2-amino-1,2-diphenylethyl)-4-methylbenzenesulfonamideHCID 13339656N-(4-chloro-3-oxo-1-phenylbutan-2-yl)benzamideHCID 178425026HCID 178425026, compound

Product 1

HCID 178523156N-(4-chloro-3-hydroxy-1-phenylbutan-2-yl)benzamide

Sources & evidence

ORD record
ord-2eed74d5fbf44d4abef77e38155af400
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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