Bicarbonate Ion → 4-(Bromomethyl)-2-(1H-pyrazol-1-YL)pyridine

Reaction equation

[CH2:18]1[O:19][CH2:20][CH2:21][CH2:22]1.[CH3:28][CH2:29][O:30][CH2:31][CH3:32].[CH3:33][CH2:34][O:35][C:36](=[O:37])[CH3:38].[Na+:27].[O-:23][C:24]([OH:25])=[O:26].[P:14]([Br:15])([Br:16])[Br:17].[n:1]1(-[c:6]2[n:7][cH:8][cH:9][c:10]([CH2:12][OH:13])[cH:11]2)[n:2][cH:3][cH:4][cH:5]1>>[n:1]1(-[c:6]2[n:7][cH:8][cH:9][c:10]([CH2:12][Br:15])[cH:11]2)[n:2][cH:3][cH:4][cH:5]1

Participants

Reactant 7

HCID 769Bicarbonate Ion

HCID 923Sodium Ion

HCID 3283Diethyl Ether

HCID 8028Tetrahydrofuran

HCID 8857Ethyl Acetate

HCID 24614Phosphorus tribromide

HCID 61256684(2-(1H-Pyrazol-1-YL)pyridin-4-YL)methanol

Product 1

Sources & evidence

ORD record: ord-c80d1c5a21824f99858cc9724172e3dc
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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