Dichloromethane → 6-chloro-N-((7-chloro-4-oxo-1-phenyl-1,4-dihydroquinolin-3-yl)methyl)nicotinamide

HRID 135890

Reaction equation

HRID 135890 reaction equation
[CH2:40]([Cl:41])[Cl:42].[CH:11]([N:12]([CH2:13][CH3:14])[CH:15]([CH3:16])[CH3:17])([CH3:18])[CH3:19].[Cl:1][c:2]1[n:3][cH:4][c:5]([C:6](=[O:7])[OH:8])[cH:9][cH:10]1.[NH2:20][CH2:21][c:22]1[cH:23][n:24](-[c:34]2[cH:35][cH:36][cH:37][cH:38][cH:39]2)[c:25]2[cH:26][c:27]([Cl:33])[cH:28][cH:29][c:30]2[c:31]1=[O:32]>>[Cl:1][c:2]1[n:3][cH:4][c:5]([C:6](=[O:8])[NH:20][CH2:21][c:22]2[cH:23][n:24](-[c:34]3[cH:35][cH:36][cH:37][cH:38][cH:39]3)[c:25]3[cH:26][c:27]([Cl:33])[cH:28][cH:29][c:30]3[c:31]2=[O:32])[cH:9][cH:10]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 792226-Chloronicotinic acidHCID 81531DiisopropylethylamineHCID 712083983-(aminomethyl)-7-chloro-1-phenylquinolin-4(1H)-one

Product 1

HCID 714870636-chloro-N-((7-chloro-4-oxo-1-phenyl-1,4-dihydroquinolin-3-yl)methyl)nicotinamide

Sources & evidence

ORD record
ord-c0d9dbf64b234a31b64b24396cec4a98
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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