Dimethylformamide → 3-(3-Methyl-butyrylamino)-pyrazine-2-carboxylic acid

HRID 136600

Reaction equation

HRID 136600 reaction equation
[C:43]([Cl:44])(=[O:45])[CH2:46][CH:47]([CH3:48])[CH3:49].[CH2:1]([NH:2][C:9](=[O:10])[c:11]1[n:12][cH:13][cH:14][n:15][c:16]1[NH:17][C:18]([CH2:19][CH:20]([CH3:21])[CH3:22])=[O:23])[c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1.[CH:34]([N:35]([CH:36]([CH3:37])[CH3:38])[CH2:39][CH3:40])([CH3:41])[CH3:42].[NH2:24][c:25]1[c:26]([C:27]([OH:28])=[O:32])[n:29][cH:30][cH:31][n:33]1.[O:50]=[CH:51][N:52]([CH3:53])[CH3:54]>>[C:9]([OH:10])([c:11]1[n:12][cH:13][cH:14][n:15][c:16]1[NH:17][C:18]([CH2:19][CH:20]([CH3:21])[CH3:22])=[O:23])=[O:32]

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 66054Isovaleryl chlorideHCID 726563-Amino-2-pyrazinecarboxylic acidHCID 81531DiisopropylethylamineHCID 693134583-(3-Methyl-butyrylamino)-pyrazine-2-carboxylic acid benzylamide

Product 1

HCID 221726023-(3-Methyl-butyrylamino)-pyrazine-2-carboxylic acid

Sources & evidence

ORD record
ord-cd16c7a6b8e94925bab3e83293e01786
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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