Dimethylamine → Dimethyl-{3-[4-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-quinolin-7-yloxy]-propyl}-amine

HRID 137235

Reaction equation

HRID 137235 reaction equation
[CH3:32][NH:33][CH3:34].[CH3:40][N:41]([CH3:42])[CH:43]=[O:44].[Cl:1][CH2:2][CH2:3][CH2:4][O:5][c:6]1[cH:7][cH:8][c:9]2[c:10](-[c:16]3[c:17]4[n:18]([n:19][c:20]3-[c:21]3[n:22][cH:23][cH:24][cH:25][cH:26]3)[CH2:27][CH2:28][CH2:29]4)[cH:11][cH:12][n:13][c:14]2[cH:15]1.[I-:31].[Na+:30].[O:35]1[CH2:36][CH2:37][CH2:38][CH2:39]1>>[CH2:2]([CH2:3][CH2:4][O:5][c:6]1[cH:7][cH:8][c:9]2[c:10](-[c:16]3[c:17]4[n:18]([n:19][c:20]3-[c:21]3[n:22][cH:23][cH:24][cH:25][cH:26]3)[CH2:27][CH2:28][CH2:29]4)[cH:11][cH:12][n:13][c:14]2[cH:15]1)[N:33]([CH3:32])[CH3:34]

Participants

7

Reactant 6

HCID 674DimethylamineHCID 923Sodium ionHCID 6228DimethylformamideHCID 8028TetrahydrofuranHCID 30165Iodide IonHCID 219925637-(3-Chloro-propoxy)-4-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-quinoline

Product 1

HCID 10112407Dimethyl-{3-[4-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-quinolin-7-yloxy]-propyl}-amine

Sources & evidence

ORD record
ord-ca6ce8c062684a5fbae1f07d3959084c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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