Dimethylformamide → 1-(2-Methoxy-4-nitro-phenyl)-4-triisopropylsilanyloxy-piperidine

HRID 137761

Reaction equation

[CH3:1][O:2][c:3]1[c:4]([N:12]2[CH2:13][CH2:14][CH:15]([OH:18])[CH2:16][CH2:17]2)[cH:5][cH:6][c:7]([N+:9](=[O:10])[O-:11])[cH:8]1.[CH3:37][CH2:38][N:39]([CH2:40][CH3:41])[CH2:42][CH3:43].[CH:19]([CH3:20])([CH3:21])[Si:22]([CH:23]([CH3:24])[CH3:25])([CH:26]([CH3:27])[CH3:28])[O:29][S:30]([C:31]([F:32])([F:33])[F:34])(=[O:35])=[O:36].[O:44]=[CH:45][N:46]([CH3:47])[CH3:48]>>[CH3:1][O:2][c:3]1[c:4]([N:12]2[CH2:13][CH2:14][CH:15]([O:18][Si:22]([CH:19]([CH3:20])[CH3:21])([CH:23]([CH3:24])[CH3:25])[CH:26]([CH3:27])[CH3:28])[CH2:16][CH2:17]2)[cH:5][cH:6][c:7]([N+:9](=[O:10])[O-:11])[cH:8]1

Participants

Reactant 4

HCID 6228Dimethylformamide

HCID 8471Triethylamine

HCID 2724529Triisopropylsilyl trifluoromethanesulfonate

HCID 574214671-(2-Methoxy-4-nitro-phenyl)-piperidin-4-ol

Product 1

HCID 575017001-(2-Methoxy-4-nitro-phenyl)-4-triisopropylsilanyloxy-piperidine

Sources & evidence

ORD record: ord-51eeb9ba07174866aa6780273be93a6c
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Linked notes

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