Benzaldehyde → N-BENZYLIDENE-2-PROPYNYLAMINE
Reaction equation
S([O-])([O-])(=O)=O.[Mg+2].[CH2:7]([NH2:10])[C:8]#[CH:9].[CH:11](=O)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>C1C=CC=CC=1>[CH:11](=[N:10][CH2:7][C:8]#[CH:9])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
10 g of magnesium sulfate was added to a stirred solution of 13.8 g of propargylamine and 26.5 g of benzaldehyde in 75 ml of benzene and the resulting mixture was stirred at room temperature for 30 minutes. The mixture then was filtered and water was removed from the filtrate by azeotropic distillation. Then the remaining benzene was evaporated and the residue was distilled to give N-benzylidene-2-propyn-1-amine (1A) b.p.: 64°-66° C. (0.2 Torr.).
Workup
- filtrationThe mixture then was filtered
- customwater was removed from the filtrate by azeotropic distillation
- customThen the remaining benzene was evaporated
- distillationthe residue was distilled
Sources & evidence
- ORD record
- ord-43ff14e1e349424181a1693c7e5d0f57
- Source dataset
- uspto-grants-1986_04
- Patent number
- US04582529
Reaction notes
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