4-Nitrobenzyl chloride → HCID 21331831, compound
Reaction equation
[N+:1]([C:4]1[CH:11]=[CH:10][C:7]([CH2:8]Cl)=[CH:6][CH:5]=1)([O-:3])=[O:2].Cl.Cl.[CH2:14]([C:16]1[CH:17]=[C:18]([N:22]2[CH2:27][CH2:26][NH:25][CH2:24][CH2:23]2)[CH:19]=[CH:20][CH:21]=1)[CH3:15]>C(N(CC)CC)C>[CH2:14]([C:16]1[CH:17]=[C:18]([N:22]2[CH2:23][CH2:24][N:25]([CH2:8][C:7]3[CH:10]=[CH:11][C:4]([N+:1]([O-:3])=[O:2])=[CH:5][CH:6]=3)[CH2:26][CH2:27]2)[CH:19]=[CH:20][CH:21]=1)[CH3:15]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
In the manner given in Example 1A, p-nitrobenzyl chloride is reacted with 1-(3-ethylphenyl)piperazine dihydrochloride in the presence of triethylamine to give 1-(3-ethylphenyl)-4-(p-nitrobenzyl)piperazine.
Sources & evidence
- ORD record