Triethylamine → 2-[4-(tert-Butyldimethylsilanyloxy)but-1-ynyl]phenylamine

Reaction equation

[C:9]([CH3:10])([CH3:11])([CH3:12])[Si:13]([CH3:14])([CH3:15])[O:16][CH2:17][CH2:18][C:19]#[CH:20].[CH3:21][CH2:22][N:23]([CH2:24][CH3:25])[CH2:26][CH3:27].[Cu:28][I:29].[I:1][c:2]1[c:3]([NH2:4])[cH:5][cH:6][cH:7][cH:8]1>>[c:2]1([C:20]#[C:19][CH2:18][CH2:17][O:16][Si:13]([C:9]([CH3:10])([CH3:11])[CH3:12])([CH3:14])[CH3:15])[c:3]([NH2:4])[cH:5][cH:6][cH:7][cH:8]1

Participants

Reactant 4

HCID 8471Triethylamine

HCID 119952-Iodoaniline

HCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)

HCID 4304567(But-3-yn-1-yloxy)(tert-butyl)dimethylsilane

Product 1

HCID 576757402-[4-(tert-Butyldimethylsilanyloxy)but-1-ynyl]phenylamine

Sources & evidence

ORD record: ord-e153d76ff34f4141a1fbc7f8bd66abfa
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Reaction notes

Loading…