Dimethylformamide → HCID 13860722, compound
Reaction equation
[NH2:1][C:2]1[CH:7]=[C:6](Cl)[CH:5]=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10].[C:12]1([S:18]([O-:20])=[O:19])[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1.[Na+].CN(C)C=O>O>[NH2:1][C:2]1[CH:7]=[C:6]([S:18]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)(=[O:20])=[O:19])[CH:5]=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
2.0 g. of 2 amino-4-chloro-1-nitrobenzene and 5.0 g. sodium benzene-sulfinate in 20 ml. dimethylformamide is heated at reflux for 3 hours. The mixture is cooled, diluted with water and the product filtered off to give 2-amino-1-nitro-4-phenylsulfonylbenzene.
Workup
- temperatureat reflux for 3 hours
- temperatureThe mixture is cooled
- filtrationthe product filtered off
Sources & evidence
- ORD record
- ord-a7b931c682a64860b4cb5ce803b1e76a
- Source dataset
- uspto-grants-1977_01
- Patent number
- US04002640
Reaction notes
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