Hydrochloric Acid → 3,3,3-Trifluoro-2-(trifluoromethyl)-1-(hydroxymethyl)propylamine

HRID 141649

Reaction equation

[CH2:17]1[O:18][CH2:19][CH2:20][CH2:21]1.[ClH:16].[F:1][C:2]([CH:3]([CH:4]([NH2:5])[C:6](=[O:7])[O:8][CH3:9])[C:10]([F:11])([F:12])[F:13])([F:14])[F:15]>>[F:1][C:2]([CH:3]([CH:4]([NH2:5])[CH2:6][OH:7])[C:10]([F:11])([F:12])[F:13])([F:14])[F:15]

Participants

Reactant 3

HCID 313Hydrochloric Acid

HCID 8028Tetrahydrofuran

HCID 13526774Methyl 2-amino-4,4,4-trifluoro-3-(trifluoromethyl)butanoate

Product 1

HCID 451079713,3,3-Trifluoro-2-(trifluoromethyl)-1-(hydroxymethyl)propylamine

Sources & evidence

ORD record: ord-41a50f9b9fd7426e992be6c454ad828d
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Linked notes

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