Chloride → [2-Amino-6-(4-methoxymethyl-oxazol-2-yl)-3-nitro-pyridin-4-yl]-benzyl-carbamic acid ethyl ester

HRID 142232

Reaction equation

HRID 142232 reaction equation
[CH2:9]([CH3:10])[O:11][C:12]([N:13]([CH2:14][c:15]1[cH:16][cH:17][cH:18][cH:19][cH:20]1)[c:21]1[c:22]([N+:29](=[O:30])[O-:31])[c:23]([NH2:28])[n:24][c:25]([Br:27])[cH:26]1)=[O:32].[CH3:1][O:2][CH2:3][c:4]1[n:5][cH:6][o:7][cH:8]1.[Cl-:33].[Cl-:34].[Pd+2:73].[c:35]1([P:36]([c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[c:43]2[cH:44][cH:45][cH:46][cH:47][cH:48]2)[cH:49][cH:50][cH:51][cH:52][cH:53]1.[c:54]1([P:55]([c:56]2[cH:57][cH:58][cH:59][cH:60][cH:61]2)[c:62]2[cH:63][cH:64][cH:65][cH:66][cH:67]2)[cH:68][cH:69][cH:70][cH:71][cH:72]1>>[CH3:1][O:2][CH2:3][c:4]1[n:5][c:6](-[c:25]2[n:24][c:23]([NH2:28])[c:22]([N+:29](=[O:30])[O-:31])[c:21]([N:13]([C:12]([O:11][CH2:9][CH3:10])=[O:32])[CH2:14][c:15]3[cH:16][cH:17][cH:18][cH:19][cH:20]3)[cH:26]2)[o:7][cH:8]1

Participants

6

Reactant 5

HCID 312Chloride2×HCID 11776Triphenylphosphine2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 230809034-Methoxymethyl-oxazoleHCID 86614485(2-Amino-6-bromo-3-nitro-pyridin-4-yl)-benzyl-carbamic acid ethyl ester

Product 1

HCID 67457819[2-Amino-6-(4-methoxymethyl-oxazol-2-yl)-3-nitro-pyridin-4-yl]-benzyl-carbamic acid ethyl ester

Sources & evidence

ORD record
ord-56887a6cb3644c089e309026dae547ee
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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