(R)-1-((5-azido-5,6,7,8-tetrahydronaphthalen-2-yl)methyl)piperidine → (R)-2-((1-((R)-6-(piperidin-1-ylmethyl)-1,2,3,4-tetrahydro-naphthalen-1-yl)-1H-1,2,3-triazol-4-yl)methyl)-1-tosyl-1,2-dihydropyrido[2,3-b]pyrazin-3(4H)-one
Reaction equation
[CH2:1]([C@@H:4]1[C:9](=[O:10])[NH:8][C:7]2[N:11]=[CH:12][CH:13]=[CH:14][C:6]=2[N:5]1[S:15]([C:18]1[CH:24]=[CH:23][C:21]([CH3:22])=[CH:20][CH:19]=1)(=[O:17])=[O:16])[C:2]#[CH:3].[N:25]([C@@H:28]1[CH2:37][CH2:36][CH2:35][C:34]2[CH:33]=[C:32]([CH2:38][N:39]3[CH2:44][CH2:43][CH2:42][CH2:41][CH2:40]3)[CH:31]=[CH:30][C:29]1=2)=[N+:26]=[N-:27]>O1CCOCC1.CC(O)(C)C.O.CCOC(C)=O.O.O.O.O.O.S([O-])([O-])(=O)=O.[Cu+2]>[N:39]1([CH2:38][C:32]2[CH:33]=[C:34]3[C:29](=[CH:30][CH:31]=2)[C@H:28]([N:25]2[CH:3]=[C:2]([CH2:1][C@@H:4]4[C:9](=[O:10])[NH:8][C:7]5[N:11]=[CH:12][CH:13]=[CH:14][C:6]=5[N:5]4[S:15]([C:18]4[CH:19]=[CH:20][C:21]([CH3:22])=[CH:23][CH:24]=4)(=[O:16])=[O:17])[N:27]=[N:26]2)[CH2:37][CH2:36][CH2:35]3)[CH2:44][CH2:43][CH2:42][CH2:41][CH2:40]1Participants
8
