4,4,5,5,5-Pentafluoropent-2-en-l-ol → 4,4,5,5,5-Pentafluoropentan-1-ol
Reaction equation
[F:1][C:2]([F:11])([C:7]([F:10])([F:9])[F:8])[CH:3]=[CH:4][CH2:5][OH:6]>C(OCC)(=O)C.[Pt](=O)=O>[F:1][C:2]([F:11])([C:7]([F:8])([F:9])[F:10])[CH2:3][CH2:4][CH2:5][OH:6]Participants
4
Reactant 1
Product 1
Reagents, catalysts & solvents 2
Procedure
A solution of 25 g of 4,4,5,5,5-pentafluoropent-2-en-l-ol (Kitazume, T. and Ishikawa, N., J. Am. Chem. Soc., (1985), p. 5186) in 100 ml of ethyl acetate is shaken with 100 mg of platinum dioxide under a hydrogen atmosphere for 1 hour. Then, the catalyst is filtered off and distilled fractionating. At 133°-135° C. 22 g of 4,4,5,5,5-pentafluoropentanol is obtained with 1H-NMR (CDCl3) δ: 1.86 (m, H2), 2.18 (m, H1) and 3.75 (t, J=6.1 Hz, H1 ) .
Workup
- filtrationThen, the catalyst is filtered off
- distillationdistilled fractionating
- customAt 133°-135° C
Sources & evidence
- ORD record
- ord-ec497f8335d54d49bd6d1534eba3a026
- Source dataset
- uspto-grants-1996_03
- Patent number
- US05502046
Reaction notes
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