Tetrahydrofuran → oxolan-3-yl N-[1-[2-(2-fluoro-6-hydroxyphenyl)-7-methylquinazolin-4-yl]pyrrolidin-3-yl]carbamate
Reaction equation
[CH2:1]([N:2]([CH:3]([CH3:4])[CH3:5])[CH:6]([CH3:7])[CH3:8])[CH3:9].[CH2:44]1[O:45][CH2:46][CH2:47][CH2:48]1.[Cl:35][C:36](=[O:37])[O:38][CH:39]1[CH2:40][O:41][CH2:42][CH2:43]1.[NH2:10][CH:11]1[CH2:12][N:13]([c:16]2[n:17][c:18](-[c:27]3[c:28]([OH:34])[cH:29][cH:30][cH:31][c:32]3[F:33])[n:19][c:20]3[cH:21][c:22]([CH3:26])[cH:23][cH:24][c:25]23)[CH2:14][CH2:15]1>>[NH:10]([CH:11]1[CH2:12][N:13]([c:16]2[n:17][c:18](-[c:27]3[c:28]([OH:34])[cH:29][cH:30][cH:31][c:32]3[F:33])[n:19][c:20]3[cH:21][c:22]([CH3:26])[cH:23][cH:24][c:25]23)[CH2:14][CH2:15]1)[C:36](=[O:37])[O:38][CH:39]1[CH2:40][O:41][CH2:42][CH2:43]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-fd8a8a4f55c645818b9968cdc252bd85
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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