C[O-].[Na+].[C:4]1([CH:10]2[CH2:18][C:17]3[C:12](=[C:13]([Cl:22])[C:14]([Cl:21])=[C:15]([O:19][CH3:20])[CH:16]=3)[C:11]2=[O:23])[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.I[CH2:25][CH3:26].C1C=CC=CC=1>O.CN(C)C=O>[CH2:25]([C:10]1([C:4]2[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:18][C:17]2[C:12](=[C:13]([Cl:22])[C:14]([Cl:21])=[C:15]([O:19][CH3:20])[CH:16]=2)[C:11]1=[O:23])[CH3:26]Sodium methoxide (1.24 g., 0.023 mole) is added portionwise to a stirred mixture of 2-phenyl-5-methoxy-6,7-dichloro-1-indanone (4.61 g., 0.015 mole), iodoethane (15.5 ml., 0.15 mole), benzene (60 ml.) and dimethylformamide (60 ml.) under nitrogen in an ice-water bath. The reaction mixture is left to come to ambient temperature over one hour, then poured into water (1 l.), the benzene layer separated, dried over anhydrous magnesium sulfate and concentrated in vacuo to give 3.23 g. of 2-ethyl-2-phenyl-5-methoxy-6,7-dichloro-1-indanone which melts at 139°-141° C. on crystallization from benzene:hexane, 1:1.
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