O-Xylene → 3-Methyl-1-[4-(trifluoromethyl)-2-pyridinyl]piperazine
Reaction equation
[CH3:1][CH:2]1[NH:3][CH2:4][CH2:5][NH:6][CH2:7]1.[Cl:8][c:9]1[n:10][cH:11][cH:12][c:13]([C:15]([F:16])([F:17])[F:18])[cH:14]1.[c:19]1([CH3:20])[c:21]([CH3:22])[cH:23][cH:24][cH:25][cH:26]1>>[CH3:1][CH:2]1[NH:3][CH2:4][CH2:5][N:6]([c:9]2[n:10][cH:11][cH:12][c:13]([C:15]([F:16])([F:17])[F:18])[cH:14]2)[CH2:7]1Participants
4
Sources & evidence
- ORD record
- ord-95ad616f53b74ccfa2a5fd454e0915aa
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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