Tetrahydrofuran → 4-(2-Benzyl-2,3-dihydro-1H-isoindol-5-yl)-tetrahydro-pyran-4-ol
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][c:10]2[cH:11][cH:12][c:13]([Br:17])[cH:14][c:15]2[CH2:16]1.[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1.[Li:18][CH2:19][CH2:20][CH2:21][CH3:22].[O:23]1[CH2:24][CH2:25][C:26](=[O:29])[CH2:27][CH2:28]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][c:10]2[cH:11][cH:12][c:13]([C:26]3([OH:29])[CH2:25][CH2:24][O:23][CH2:28][CH2:27]3)[cH:14][c:15]2[CH2:16]1Participants
5
Sources & evidence
- ORD record
- ord-f87337bcca0c443392158fe002d6f4c1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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