Tetrahydrofuran → 2-[2-(4-Chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-(4,4-difluoro-cyclohexyl)-ethanol
Reaction equation
[Al+3:32].[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[c:11]([n:12]2[CH:13]([C:14](=[O:15])[OH:16])[CH:17]2[CH2:18][CH2:19][C:20]([F:23])([F:24])[CH2:21][CH2:22]2)[cH:25][c:26]([F:30])[c:27]([F:29])[cH:28]3)[cH:6][cH:7]1.[H-:31].[H-:34].[H-:35].[H-:36].[Li+:33].[O:37]1[CH2:38][CH2:39][CH2:40][CH2:41]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[c:11]([n:12]2[CH:13]([CH2:14][OH:15])[CH:17]2[CH2:18][CH2:19][C:20]([F:23])([F:24])[CH2:21][CH2:22]2)[cH:25][c:26]([F:30])[c:27]([F:29])[cH:28]3)[cH:6][cH:7]1
