O-Xylene → HCID 18428552, compound

Reaction equation

C([OH:6])/C=C\CC.[H-].[Na+].[Cl:9][C:10]([Cl:14])([Cl:13])[C:11]#[N:12].[C:15]1([CH3:22])[C:16](C)=[CH:17]C=C[CH:20]=1>>[Cl:9][C:10]([Cl:14])([Cl:13])[C:11]([NH:12][CH2:22][C:15](=[CH2:20])[CH2:16][CH3:17])=[O:6]

Participants

Reactant 4

HCID 7237O-Xylene

HCID 11011Trichloroacetonitrile

HCID 24758Sodium hydride

HCID 5364919cis-Pent-2-ene-1-ol

Product 1

HCID 18428552HCID 18428552, compound

Procedure

Cis-2-pentene-1-ol was treated with NaH and trichloroacetonitrile followed by work up and treatment in refluxing xylene by the method of EXAMPLE 208 to produce the material.

Workup

customto produce the material

Sources & evidence

ORD record: ord-b0d84500858d4adb99427d33e44b70a6
Source dataset: uspto-grants-1998_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05854234

Reaction notes

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