Toluene → 4-Chloro-6-iodoquinazoline

HRID 147287

Reaction equation

HRID 147287 reaction equation
[CH3:18][CH2:19][N:20]([CH2:21][CH3:22])[CH2:23][CH3:24].[CH3:25][c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1.[I:1][c:2]1[cH:3][c:4]2[c:5](=[O:12])[nH:6][cH:7][n:8][c:9]2[cH:10][cH:11]1.[P:13]([Cl:14])([Cl:15])([Cl:16])=[O:17]>>[I:1][c:2]1[cH:3][c:4]2[c:5]([Cl:15])[n:6][cH:7][n:8][c:9]2[cH:10][cH:11]1

Participants

5

Reactant 4

HCID 1140TolueneHCID 8471TriethylamineHCID 24813Phosphorus oxychlorideHCID 1354016666-Iodoquinazolin-4-one

Product 1

HCID 111738094-Chloro-6-iodoquinazoline

Sources & evidence

ORD record
ord-e18d4d9111ef4b7aa355ed48a7f4d1fa
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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