Dimethylformamide → N-(2-ethylphenyl)-2-(1H-indol-3-yl)-2-oxoacetamide

Reaction equation

[CH2:1]([CH3:2])[c:3]1[c:4]([NH2:5])[cH:6][cH:7][cH:8][cH:9]1.[CH:10]([N:11]([CH2:12][CH3:13])[CH:14]([CH3:15])[CH3:16])([CH3:17])[CH3:18].[O:33]=[CH:34][N:35]([CH3:36])[CH3:37].[nH:19]1[cH:20][c:21]([C:28]([C:29](=[O:30])[Cl:31])=[O:32])[c:22]2[cH:23][cH:24][cH:25][cH:26][c:27]12>>[CH2:1]([CH3:2])[c:3]1[c:4]([NH:5][C:29]([C:28]([c:21]2[cH:20][nH:19][c:27]3[c:22]2[cH:23][cH:24][cH:25][cH:26]3)=[O:32])=[O:30])[cH:6][cH:7][cH:8][cH:9]1

Participants

Reactant 4

HCID 6228Dimethylformamide

HCID 113572-Ethylaniline

HCID 81531Diisopropylethylamine

HCID 899523-Indoleglyoxylyl chloride

Product 1

HCID 3620873N-(2-ethylphenyl)-2-(1H-indol-3-yl)-2-oxoacetamide

Sources & evidence

ORD record: ord-58e5c5012f474b6c9fe3dde7fe730b6c
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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