N-methyl-2-pyrrolidone → Tert-butyl 3-[[6-[(2-chloro-4-pyridinyl)oxy]-1,3-benzothiazol-2-yl]amino]piperidine-1-carboxylate

HRID 148695

Reaction equation

HRID 148695 reaction equation
[CH3:44][N:45]1[CH2:46][CH2:47][CH2:48][C:49]1=[O:50].[CH:35]([N:36]([CH2:37][CH3:38])[CH:39]([CH3:40])[CH3:41])([CH3:42])[CH3:43].[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([O:8][c:9]2[cH:10][c:11]3[c:12]([n:13][c:14]([S:16]([CH3:17])=[O:18])[s:15]3)[cH:19][cH:20]2)[cH:7]1.[NH2:21][CH:22]1[CH2:23][N:24]([C:28](=[O:29])[O:30][C:31]([CH3:32])([CH3:33])[CH3:34])[CH2:25][CH2:26][CH2:27]1>>[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([O:8][c:9]2[cH:10][c:11]3[c:12]([n:13][c:14]([NH:21][CH:22]4[CH2:23][N:24]([C:28](=[O:29])[O:30][C:31]([CH3:32])([CH3:33])[CH3:34])[CH2:25][CH2:26][CH2:27]4)[s:15]3)[cH:19][cH:20]2)[cH:7]1

Participants

5

Reactant 4

HCID 13387N-methyl-2-pyrrolidoneHCID 81531DiisopropylethylamineHCID 5458091-BOC-3-AminopiperidineHCID 577254306-(2-Chloropyridin-4-yloxy)-2-(methylsulfinyl)benzo[d]thiazole

Product 1

HCID 87421241Tert-butyl 3-[[6-[(2-chloro-4-pyridinyl)oxy]-1,3-benzothiazol-2-yl]amino]piperidine-1-carboxylate

Sources & evidence

ORD record
ord-456c5851122740b28194884947a196d4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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