2-Methylbenzoxazole → 2-Methyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-benzoxazole

HRID 1490427

Reaction equation

HRID 1490427 reaction equation
Cc1nc2ccccc2o1>C1=CCCC=CCC1.C1=CCCC=CCC1.C1CCOC1.CC(C)(C)c1ccnc(-c2cc(C(C)(C)C)ccn2)c1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.C[OH2+].C[OH2+].[Ir].[Ir]>Cc1nc2cccc(B3OC(C)(C)C(C)(C)O3)c2o1

Participants

6

Reactant 1

HCID 72252-Methylbenzoxazole

Product 1

HCID 569731272-Methyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-benzoxazoleYield 43%

Reagents, catalysts & solvents 4

HCID 2733548Bis(pinacolato)diboraneReagentHCID 42491874,4'-Di-tert-butyl-2,2'-bipyridylReagentHCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridiumCatalystHCID 8028TetrahydrofuranSolvent

Conditions

Temperature
25 °C

Sources & evidence

ORD record
ord-04960d6e779e4313ae5e098dc259e93c
Source dataset
Borylation dataset from Roche

Linked notes

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