6-Methoxyquinoline-2-carbonitrile → HCID 178487953, compound

HRID 1490909

Reaction equation

HRID 1490909 reaction equation
COc1ccc2nc(C#N)ccc2c1>C1=CCCC=CCC1.C1=CCCC=CCC1.CC(C)(C)c1ccnc(-c2cc(C(C)(C)C)ccn2)c1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.COC(C)(C)C.C[OH2+].C[OH2+].[Ir].[Ir]>COc1ccc2nc(C#N)cc(B3OC(C)(C)C(C)(C)O3)c2c1

Participants

6

Reactant 1

HCID 2304816-Methoxyquinoline-2-carbonitrile

Product 1

HCID 178487953HCID 178487953, compoundYield 83%

Reagents, catalysts & solvents 4

HCID 2733548Bis(pinacolato)diboraneReagentHCID 42491874,4'-Di-tert-butyl-2,2'-bipyridylReagentHCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridiumCatalystHCID 15413tert-Butyl methyl etherSolvent

Conditions

Temperature
100 °C

Procedure

-

Sources & evidence

ORD record
ord-8fd3d72ce4fa45d9ba808182a3ff2c07
Source dataset
Borylation dataset from Roche

Linked notes

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