Tetrahydrofuran → 1-(2-Aminoethyl)piperidin-4-ol
Reaction equation
[Al+3:22].[CH2:27]1[O:28][CH2:29][CH2:30][CH2:31]1.[H-:21].[H-:24].[H-:25].[H-:26].[Li+:23].[NH2:1][CH2:2][CH2:3][N:4]1[CH2:5][CH2:6][CH2:7][CH:8]([OH:9])[CH2:10]1.[OH:11][CH:12]1[CH2:13][CH2:14][N:15]([CH2:18][C:19]#[N:20])[CH2:16][CH2:17]1>>[OH:11][CH:12]1[CH2:13][CH2:14][N:15]([CH2:18][CH2:19][NH2:20])[CH2:16][CH2:17]1Participants
7
Sources & evidence
- ORD record
- ord-ddd3b27bf0e34a00bfd275091a309f73
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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