Phenol → [(R)-2-(7-nitro-5-phenoxymethyl-1H-indol-2-yl)-4,5-dihydro-thiazol-4-yl]-acetic acid methyl ester

Reaction equation

[C:1]1([OH:7])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[H-].[Na+].[CH3:10][O:11][C:12](=[O:33])[CH2:13][C@@H:14]1[CH2:18][S:17][C:16]([C:19]2[NH:20][C:21]3[C:26]([CH:27]=2)=[CH:25][C:24]([CH2:28]Cl)=[CH:23][C:22]=3[N+:30]([O-:32])=[O:31])=[N:15]1.[NH4+].[Cl-]>CN(C=O)C>[CH3:10][O:11][C:12](=[O:33])[CH2:13][C@@H:14]1[CH2:18][S:17][C:16]([C:19]2[NH:20][C:21]3[C:26]([CH:27]=2)=[CH:25][C:24]([CH2:28][O:7][C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)=[CH:23][C:22]=3[N+:30]([O-:32])=[O:31])=[N:15]1