Tetrahydrofuran → 2-Benzimidazol-2-yl-N-(4-cyano(3-pyridyl))acetamide

HRID 154333

Reaction equation

[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[CH3:2][Si:3]([N-:4][Si:5]([CH3:6])([CH3:7])[CH3:8])([CH3:9])[CH3:10].[Li+:1].[NH2:26][c:27]1[cH:28][n:29][cH:30][cH:31][c:32]1[C:33]#[N:34].[n:11]1[c:12]([CH2:20][C:21]([O:23][CH2:22][CH3:24])=[O:25])[nH:13][c:14]2[c:15]1[cH:16][cH:17][cH:18][cH:19]2>>[nH:11]1[c:12]([CH2:20][C:21](=[O:23])[NH:26][c:27]2[cH:28][n:29][cH:30][cH:31][c:32]2[C:33]#[N:34])[n:13][c:14]2[c:15]1[cH:16][cH:17][cH:18][cH:19]2

Participants

Reactant 5

HCID 8028Tetrahydrofuran

HCID 28486Lithium ion

HCID 308071ethyl 2-(1H-1,3-benzodiazol-2-yl)acetate

HCID 3280088Npc316347

HCID 106782193-Aminopyridine-4-carbonitrile

Product 1

HCID 129887822-Benzimidazol-2-yl-N-(4-cyano(3-pyridyl))acetamide

Sources & evidence

ORD record: ord-69dc0124762549a3aa27f688845b17c7
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Linked notes

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