Chloride → 2-Bromo-5-[2-(4-fluorophenyl)ethenyl]thiophene

HRID 1543984

Reaction equation

HRID 1543984 reaction equation
[Br:34][c:35]1[cH:36][cH:37][c:38]([CH:40]=[O:41])[s:39]1.[CH2:43]1[O:44][CH2:45][CH2:46][CH2:47]1.[CH3:29][CH2:30][CH2:31][CH2:32][Li:33].[Cl-:1].[F:2][c:3]1[cH:4][cH:5][c:6]([CH2:7][P+:8]([c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)([c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[cH:27][cH:28]1.[OH2:42]>>[F:2][c:3]1[cH:4][cH:5][c:6]([CH:7]=[CH:40][c:38]2[cH:37][cH:36][c:35]([Br:34])[s:39]2)[cH:27][cH:28]1

Participants

7

Reactant 6

HCID 312ChlorideHCID 962WaterHCID 8028TetrahydrofuranHCID 784285-Bromothiophene-2-carbaldehydeHCID 2733555(4-Fluorophenyl)methyl-triphenylphosphaniumHCID 178418339Butyllithium

Product 1

HCID 698920002-Bromo-5-[2-(4-fluorophenyl)ethenyl]thiophene

Sources & evidence

ORD record
ord-bae95345cb014d56a77622b2ac1fdb36
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Linked notes

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