Tetrahydrofuran → 2,6-Difluoro-N-(1-{[5-(phenyloxy)-2-(trifluoromethyl)phenyl]methyl}-1H-pyrazol-3-yl)benzamide
Reaction equation
[Br:27][CH2:28][c:29]1[c:30]([C:42]([F:43])([F:44])[F:45])[cH:31][cH:32][c:33]([O:35][c:36]2[cH:37][cH:38][cH:39][cH:40][cH:41]2)[cH:34]1.[CH2:46]1[O:47][CH2:48][CH2:49][CH2:50]1.[CH3:17][Si:18]([N-:19][Si:20]([CH3:21])([CH3:22])[CH3:23])([CH3:24])[CH3:25].[F:1][c:2]1[c:3]([C:4](=[O:5])[NH:6][c:7]2[n:8][nH:9][cH:10][cH:11]2)[c:12]([F:16])[cH:13][cH:14][cH:15]1.[Li+:26]>>[F:1][c:2]1[c:3]([C:4](=[O:5])[NH:6][c:7]2[n:8][n:9]([CH2:28][c:29]3[c:30]([C:42]([F:43])([F:44])[F:45])[cH:31][cH:32][c:33]([O:35][c:36]4[cH:37][cH:38][cH:39][cH:40][cH:41]4)[cH:34]3)[cH:10][cH:11]2)[c:12]([F:16])[cH:13][cH:14][cH:15]1
