Tetrahydrofuran → N-butyl-N-(1,1-dioxo-2,3-dihydro-1H-benzo[b]thiophen-3-yl)methanesulfonamide

Reaction equation

[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[CH2:6]([CH2:7][CH2:8][CH3:9])[NH:10][CH:11]1[c:12]2[c:13]([cH:18][cH:19][cH:20][cH:21]2)[S:14](=[O:16])(=[O:17])[CH2:15]1.[CH3:1][S:2]([Cl:3])(=[O:4])=[O:5].[CH3:22][CH2:23][N:24]([CH2:25][CH3:26])[CH2:27][CH3:28]>>[CH3:1][S:2](=[O:4])(=[O:5])[N:10]([CH2:6][CH2:7][CH2:8][CH3:9])[CH:11]1[c:12]2[c:13]([cH:18][cH:19][cH:20][cH:21]2)[S:14](=[O:16])(=[O:17])[CH2:15]1

Participants

Reactant 4

HCID 8028Tetrahydrofuran

HCID 8471Triethylamine

HCID 31297Methanesulfonyl chloride

HCID 19365895butyl-(1,1-dioxo-2,3-dihydro-1H-benzo[b]thiophen-3-yl)-amine

Product 1

HCID 9926984N-butyl-N-(1,1-dioxo-2,3-dihydro-1H-benzo[b]thiophen-3-yl)methanesulfonamide

Sources & evidence

ORD record: ord-e2490303ef8047eb912f41938fad1054
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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