Chloride → N-Boc-N-methyl-2-(pyridin-2-yl)ethanamine

Reaction equation

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH2:9][CH2:10][c:11]1[n:12][cH:13][cH:14][cH:15][cH:16]1.[CH3:19][I:20].[CH3:23][N:24]([CH3:25])[CH:26]=[O:27].[Cl-:22].[H-:17].[Na+:18].[Na+:21].[OH2:28]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]([CH2:9][CH2:10][c:11]1[n:12][cH:13][cH:14][cH:15][cH:16]1)[CH3:19]

Participants

Reactant 7

HCID 312Chloride

HCID 923Sodium Ion2×

HCID 962Water

HCID 6228Dimethylformamide

HCID 6328Methyl iodide

HCID 166653Hydride

HCID 22027815tert-Butyl [2-(pyridin-2-yl)ethyl]carbamate

Product 1

HCID 18988032N-Boc-N-methyl-2-(pyridin-2-yl)ethanamine

Sources & evidence

ORD record: ord-f175d15b51dd4ee98bb3e977cbda1ae7
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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