Hydrochloric Acid → 3-amino-8-(2-oxopyrrolidin-1-yl)-1-(thiophen-3-ylmethyl)-3,4-dihydroquinolin-2(1H)-one
Reaction equation
[C:33](=[O:34])([OH:35])[O-:36].[CH3:38][CH2:39][O:40][C:41](=[O:42])[CH3:43].[ClH:32].[K+:37].[O:1]=[C:2]1[N:3]([CH2:26][c:27]2[cH:28][s:29][cH:30][cH:31]2)[c:4]2[c:5]([N:20]3[C:21](=[O:25])[CH2:22][CH2:23][CH2:24]3)[cH:6][cH:7][cH:8][c:9]2[CH2:10][CH:11]1[NH:12][C:13](=[O:14])[O:15][C:16]([CH3:17])([CH3:18])[CH3:19].[OH2:44]>>[O:1]=[C:2]1[N:3]([CH2:26][c:27]2[cH:28][s:29][cH:30][cH:31]2)[c:4]2[c:5]([N:20]3[C:21](=[O:25])[CH2:22][CH2:23][CH2:24]3)[cH:6][cH:7][cH:8][c:9]2[CH2:10][CH:11]1[NH2:12]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-617645d0586d4bd89ad9a0343b9ca6cd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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