Sodium Ion → 7H-Pyrrolo(2,3-d)pyrimidine

Reaction equation

[CH:21]([Si:22]([Cl:23])([CH:24]([CH3:25])[CH3:26])[CH:27]([CH3:28])[CH3:29])([CH3:30])[CH3:31].[Cl:11][c:12]1[n:13][cH:14][c:15]2[cH:16][cH:17][nH:18][c:19]2[n:20]1.[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[nH:8][cH:9][cH:10]2.[H-:32].[Na+:33].[O:34]1[CH2:35][CH2:36][CH2:37][CH2:38]1>>[cH:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[nH:8][cH:9][cH:10]2

Participants

Reactant 6

HCID 923Sodium Ion

HCID 8028Tetrahydrofuran

HCID 139400Triisopropylsilyl chloride

HCID 166653Hydride

HCID 53566827H-Pyrrolo(2,3-d)pyrimidine, 4-chloro-

HCID 57067742-Chloro-7H-pyrrolo[2,3-d]pyrimidine

Product 1

HCID 2615917H-Pyrrolo(2,3-d)pyrimidine

Sources & evidence

ORD record: ord-a0eb347f9d4c499fbc95bc7538fad876
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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