Piperazine → 8-Chloro-5,11-dihydro-11-(1-piperazinyl)[1]benzothiepino[4,3-b]pyridine

Reaction equation

[CH2:18]1[CH2:19][NH:20][CH2:21][CH2:22][NH:23]1.[CH2:24]1[O:25][CH2:26][CH2:27][CH2:28]1.[Cl:1][c:2]1[cH:3][c:4]2[c:5]([cH:16][cH:17]1)[CH:6]([Cl:15])[c:7]1[n:8][cH:9][cH:10][cH:11][c:12]1[CH2:13][S:14]2>>[Cl:1][c:2]1[cH:3][c:4]2[c:5]([cH:16][cH:17]1)[CH:6]([N:20]1[CH2:19][CH2:18][NH:23][CH2:22][CH2:21]1)[c:7]1[n:8][cH:9][cH:10][cH:11][c:12]1[CH2:13][S:14]2

Participants

Reactant 3

HCID 4837Piperazine

HCID 8028Tetrahydrofuran

HCID 15280235HCID 15280235, compound

Product 1

HCID 157805018-Chloro-5,11-dihydro-11-(1-piperazinyl)[1]benzothiepino[4,3-b]pyridine

Sources & evidence

ORD record: ord-478e39023d244be3acaf8970f8822853
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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