Hydrochloric Acid → 2-Amino-5-chloro-4-(4-pyridylthiomethyl)thiazole

Reaction equation

[CH3:24][CH2:25][OH:26].[Cl:1][c:2]1[c:3]([CH2:10][S:11][c:12]2[cH:13][cH:14][n:15][cH:16][cH:17]2)[n:4][c:5]([NH:7][CH:8]=[O:9])[s:6]1.[ClH:23].[O:18]1[CH2:19][CH2:20][CH2:21][CH2:22]1>>[Cl:1][c:2]1[c:3]([CH2:10][S:11][c:12]2[cH:13][cH:14][n:15][cH:16][cH:17]2)[n:4][c:5]([NH2:7])[s:6]1

Participants

Reactant 4

HCID 313Hydrochloric Acid

HCID 702Ethanol

HCID 8028Tetrahydrofuran

HCID 157291695-Chloro-2-formylamino-4-(4-pyridylthiomethyl)thiazole

Product 1

HCID 189547322-Amino-5-chloro-4-(4-pyridylthiomethyl)thiazole

Sources & evidence

ORD record: ord-cb3828553d4f40bbb2bdcb0a0bced142
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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