Hydrochloric Acid → 3-{[7-(3-chloropropoxy)-6-methoxyquinazolin-4-yl]amino}-N-(3-fluorophenyl)-1H-pyrazole-5-carboxamide
Reaction equation
[CH3:44][C:45]([N:46]([CH3:47])[CH3:48])=[O:49].[Cl:23][c:24]1[n:25][cH:26][n:27][c:28]2[cH:29][c:30]([O:36][CH2:37][CH2:38][CH2:39][Cl:40])[c:31]([O:34][CH3:35])[cH:32][c:33]12.[Cl:41][CH2:42][Cl:43].[ClH:50].[NH2:1][c:2]1[n:3][nH:4][c:5]([C:7](=[O:8])[NH:9][c:10]2[cH:11][c:12]([F:16])[cH:13][cH:14][cH:15]2)[cH:6]1.[O:17]1[CH2:18][CH2:19][O:20][CH2:21][CH2:22]1>>[NH:1]([c:2]1[n:3][nH:4][c:5]([C:7](=[O:8])[NH:9][c:10]2[cH:11][c:12]([F:16])[cH:13][cH:14][cH:15]2)[cH:6]1)[c:24]1[n:25][cH:26][n:27][c:28]2[cH:29][c:30]([O:36][CH2:37][CH2:38][CH2:39][Cl:40])[c:31]([O:34][CH3:35])[cH:32][c:33]12Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-8c96a6ca97a048efa4f7de8cbdd739ca
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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