HomeMCPWorkbenchSkills
HomeWorkbenchNotificationsMe
llms.txt · MCP GuidePrivacy Policy · Terms of Service · Supportv1.8.0
  1. Home
  2. /Reaction

Potassium Iodide → HCID 515414, compound

HRID 1578660
Notes
Print preview

Reaction equation

HRID 1578660 reaction equation
Cl[CH2:2][CH2:3][CH2:4][CH2:5][C:6]([C:8]1[CH:21]=[CH:20][C:19]2[S:18][C:17]3[C:12](=[CH:13][C:14]([C:22](=[O:28])[CH2:23][CH2:24][CH2:25][CH2:26]Cl)=[CH:15][CH:16]=3)[CH2:11][C:10]=2[CH:9]=1)=[O:7].[I-].[K+].[NH:31]1[CH2:36][CH2:35][CH2:34][CH2:33][CH2:32]1>O1CCCC1>[N:31]1([CH2:2][CH2:3][CH2:4][CH2:5][C:6]([C:8]2[CH:21]=[CH:20][C:19]3[S:18][C:17]4[C:12](=[CH:13][C:14]([C:22](=[O:28])[CH2:23][CH2:24][CH2:25][CH2:26][N:31]5[CH2:36][CH2:35][CH2:34][CH2:33][CH2:32]5)=[CH:15][CH:16]=4)[CH2:11][C:10]=3[CH:9]=2)=[O:7])[CH2:36][CH2:35][CH2:34][CH2:33][CH2:32]1
ParticipantsConditionsProcedureWorkupSources & evidenceReaction notes

Participants

5

Reactant 3

HCID 4875Potassium IodideHCID 8082PiperidineHCID 12340289HCID 12340289, compound

Product 1

HCID 515414HCID 515414, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Conditions

Temperature
100 °C

Procedure

A mixture of 20 g of 2,7Bis(5-chlorovaleryl)thioxanthene, 2 g of potassium iodide, 70 ml of piperidine and 150 ml of tetrahydrofuran is heated in a Paar bomb at 100°C with stirring for 48 hours. Upon cooling, the solvent is evaporated, and the remaining material is poured into water then filtered. The residue is recrystallized several times from heptane to give 2,7-bis(5-piperidinovaleryl)thioxanthene, M.P. 98.5°-99.5°C.

Workup

  1. temperatureUpon cooling
  2. customthe solvent is evaporated
  3. additionthe remaining material is poured into water
  4. filtrationthen filtered
  5. customThe residue is recrystallized several times from heptane

Sources & evidence

ORD record
ord-73a247c39f4540bbb0b7eaf22f104249
Source dataset
uspto-grants-1976_02
DOI
10.6084/m9.figshare.5104873.v1
Patent number
US03937833

Reaction notes

Loading…

On this pageParticipantsConditionsProcedureWorkupSources & evidenceReaction notes