Hydrochloric Acid → Phenol, 2-(diethoxymethyl)-
Reaction equation
[CH:1](=[O:9])[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4].[CH2:10]([O:12]C(O)O)[CH3:11].Cl.[CH2:17](O)[CH3:18]>>[CH2:17]([O:9][CH:1]([O:12][CH2:10][CH3:11])[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4])[CH3:18]Participants
5
Procedure
A mixture of 122 parts of salicylaldehyde, 180 parts of orthoformic acid ethyl ester and 120 parts of anhydrous ethanol was mixed with 1 ml of concentrated hydrochloric acid, whereupon the whole heated up spontaneously. After a short time, the solution was heated to the boil and then evaporated under vacuum, and the residue distilled under a high vacuum. The product passed over at 80°C under 0.15mm Hg pressure.
Workup
- temperatureheated up spontaneously
- temperatureAfter a short time, the solution was heated to the boil
- customevaporated under vacuum
- distillationthe residue distilled under a high vacuum
- custompassed over at 80°C under 0.15mm Hg pressure
Sources & evidence
- ORD record
- ord-11b165ad0bc14f2a98a947048166ebb0
- Source dataset
- uspto-grants-1976_01
- Patent number
- US03933858
Reaction notes
Loading…