R-(+)-8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepine-7-ol → HCID 178465776, compound

HRID 1581294Notes

Reaction equation

HRID 1581294 reaction equation
CC(Cl)c1cccnc1.CN1CCc2cc(Cl)c(O)cc2[C@@H](c2ccccc2)C1>CN(C)C=O.O=C([O-])[O-].[Cs+].[Cs+].[I-].[K+]>CC(Oc1cc2c(cc1Cl)CCN(C)C[C@H]2c1ccccc1)c1cccnc1

Participants

6

Reactant 2

HCID 3036864R-(+)-8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepine-7-olHCID 149329503-(1-Chloroethyl)pyridine

Product 1

HCID 178465776HCID 178465776, compound

Reagents, catalysts & solvents 3

HCID 4875Potassium IodideReagentHCID 10796Cesium carbonateReagentHCID 6228DimethylformamideSolvent3×

Conditions

Temperature
70 °C

Workup

  1. aliquotNo procedure recorded
  2. additionDilution of the aliquot (2 uL) with DMSO (200 uL).

Sources & evidence

ORD record
ord-c97ccc9caff1400088b4e4027ef94cfc
Source dataset
Fig 7 data from Golden paper
Original link
View source

Reaction notes

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