Sodium Ion → (2'-Fluoro-5'-(methyloxy)-2-(2-methylpropyl)-1,1'-biphenyl-4-yl) methanol

Reaction equation

[Al+3:30].[CH2:24]1[O:25][CH2:26][CH2:27][CH2:28]1.[F:1][c:2]1[c:3](-[c:10]2[c:11]([CH2:20][CH:21]([CH3:22])[CH3:23])[cH:12][c:13]([C:16](=[O:17])[O:18][CH3:19])[cH:14][cH:15]2)[cH:4][c:5]([O:8][CH3:9])[cH:6][cH:7]1.[H-:29].[H-:32].[H-:33].[H-:34].[Li+:31].[Na+:36].[OH-:35]>>[F:1][c:2]1[c:3](-[c:10]2[c:11]([CH2:20][CH:21]([CH3:22])[CH3:23])[cH:12][c:13]([CH2:16][OH:17])[cH:14][cH:15]2)[cH:4][c:5]([O:8][CH3:9])[cH:6][cH:7]1

Participants

Reactant 7

HCID 923Sodium Ion

HCID 961Hydroxide

HCID 8028Tetrahydrofuran

HCID 28486Lithium ion

HCID 104727Aluminum Cation

HCID 166653Hydride4×

HCID 57706197Methyl 2'-fluoro-5'-(methyloxy)-2-(2-methylpropyl)-1,1'-biphenyl-4-carboxylate

Product 1

Sources & evidence

ORD record: ord-5a09440d6f53495484435093cd417e0e
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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