Chlorotrimethylsilane → HCID 68574804, compound

HRID 160251

Reaction equation

HRID 160251 reaction equation
[CH2:13]([Li:14])[CH2:15][CH2:16][CH3:17].[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[CH:6]1[C:7](=[O:12])[NH:8][CH2:9][CH2:10][CH2:11]1.[CH2:31]([CH3:32])[O:33][C:34]([CH2:35][Br:36])=[O:37].[CH3:18][Si:19]([Cl:20])([CH3:21])[CH3:22].[CH:23]([N-:24][CH:25]([CH3:26])[CH3:27])([CH3:28])[CH3:29].[Li+:30].[O:38]1[CH2:39][CH2:40][CH2:41][CH2:42]1>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[C:6]1([CH2:35][C:34]([O:33][CH2:31][CH3:32])=[O:37])[C:7](=[O:12])[NH:8][CH2:9][CH2:10][CH2:11]1

Participants

8

Reactant 7

HCID 6397ChlorotrimethylsilaneHCID 7748Ethyl bromoacetateHCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 977733-Carbethoxy-2-piperidoneHCID 5062348DiisopropylamideHCID 178418339Butyllithium

Product 1

HCID 68574804HCID 68574804, compound

Sources & evidence

ORD record
ord-aefcab99c46d4f94a8ad2aa486b060ef
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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