Acetonitrile → 3-[(5-bromo-2-chloro-pyrimidin-4-yl)-ethyl-amino]-N-methyl-propanamide

Reaction equation

[Br:1][c:2]1[c:3]([Cl:9])[n:4][c:5]([Cl:8])[n:6][cH:7]1.[CH2:10]([CH3:11])[NH:12][CH2:13][CH2:14][C:15](=[O:16])[NH:17][CH3:18].[CH3:19][CH2:20][N:21]([CH2:22][CH3:23])[CH2:24][CH3:25].[CH3:26][C:27]#[N:28]>>[Br:1][c:2]1[c:3]([N:12]([CH2:10][CH3:11])[CH2:13][CH2:14][C:15](=[O:16])[NH:17][CH3:18])[n:4][c:5]([Cl:8])[n:6][cH:7]1

Participants

Reactant 4

HCID 6342Acetonitrile

HCID 8471Triethylamine

HCID 2899735-Bromo-2,4-dichloropyrimidine

HCID 618617253-(ethylamino)-N-methylpropanamide

Product 1

HCID 866175683-[(5-bromo-2-chloro-pyrimidin-4-yl)-ethyl-amino]-N-methyl-propanamide

Sources & evidence

ORD record: ord-c304d6e474d14f9eb74f4604138676ee
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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