1,1-Dimethylhydrazine → 3-Furfurylamino-4-chloro-5-methylsulfinylbenzoic acid 2,2-diethylhydrazide

HRID 1606624

Reaction equation

[C:1](N)(=O)/[CH:2]=C/C.CN(N)C.C(NC(=O)/C=C(\O[C:21](=[O:39])[C:22]1[CH:27]=[C:26]([S:28]([CH3:30])=[O:29])[C:25]([Cl:31])=[C:24]([NH:32][CH2:33][C:34]2[O:38][CH:37]=[CH:36][CH:35]=2)[CH:23]=1)/C)(C)(C)C.C([NH:43][NH:44][CH2:45][CH3:46])C>>[CH2:1]([N:44]([CH2:45][CH3:46])[NH:43][C:21](=[O:39])[C:22]1[CH:27]=[C:26]([S:28]([CH3:30])=[O:29])[C:25]([Cl:31])=[C:24]([NH:32][CH2:33][C:34]2[O:38][CH:37]=[CH:36][CH:35]=2)[CH:23]=1)[CH3:2]

Participants

Reactant 4

HCID 59761,1-Dimethylhydrazine

HCID 153741,2-Diethylhydrazine

HCID 53544872-Butenamide

HCID 68136665N-tert-butyl-3-(3-furfurylamino-4-chloro-5-methylsulfinylbenzoyloxy)crotonamide

Product 1

HCID 538907613-Furfurylamino-4-chloro-5-methylsulfinylbenzoic acid 2,2-diethylhydrazide

Procedure

By replacing the crotonamide and the unsymmetrical-dimethylhydrazine employed in Example 38 by equimolar quantities of N-tert-butyl-3-(3-furfurylamino-4-chloro-5-methylsulfinylbenzoyloxy)crotonamide and unsymmetrical-diethylhydrazine respectively and then following substantially the same procedure described in Example 38 there is obtained 3-furfurylamino-4-chloro-5-methylsulfinylbenzoic acid 2,2-diethylhydrazide.

Sources & evidence

ORD record: ord-f0495342c44d4893b56747ec0197063f
Source dataset: uspto-grants-1976_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03953476

Linked notes

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