Ethylamine hydrochloride → 4-Bromo-N-ethyl-2-fluorobenzamide

HRID 16111

Reaction equation

HRID 16111 reaction equation
[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=O)=[C:4]([F:11])[CH:3]=1.Cl.[CH2:13]([NH2:15])[CH3:14]>C(N(CC)CC)C>[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([NH:15][CH2:13][CH3:14])=[O:8])=[C:4]([F:11])[CH:3]=1

Participants

4

Reactant 2

HCID 11198Ethylamine hydrochlorideHCID 3026814-Bromo-2-fluorobenzoic acid

Product 1

HCID 246907014-Bromo-N-ethyl-2-fluorobenzamide

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

The sub-title compound was prepared by the method of example 18 step a) using 4-bromo-2-fluorobenzoic acid, ethylamine hydrochloride and triethylamine.

Sources & evidence

ORD record
ord-ffb9776517e246d191b666a66a7c7ed0
Source dataset
uspto-grants-2010_06
Patent number
US07737135B2

Linked notes

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